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Stem cells are relatively undifferentiated cells which are the permanent lineage ancestor cells of tissues. Newly developed molecular biological techniques and probes have made possible dramatic advances in our ability to study the lineage development of stem cells. A major impetus to develop these techniques has been to identify specific stem cells for gene therapy purposes. The role that stem cells play in the development of cancer is also an important area. This book provides up-to-date reviews on a wide variety of stem cell systems by world experts. Chapters range from descriptions of the current knowledge of the biology of stem cells, to current molecular biological approaches and clinical implications. Oncologists and cell biologists will find this book of particular interest. It will also be usefule to radiobiologist, biotechnologists, and gene therapists. Key Features * Provides reviews of stem cell systems by world experts * Covers stem cell biology in plants, invertebrates, and mammals * Presents clinical implications of stem cell differentiation.
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Human genetics --- Human genetics --- Human genetics --- Human genetics --- Human genetics --- Human genetics --- Human genetics --- Human genetics --- Human genetics --- Government policy --- Government policy --- Government policy --- Moral and ethical aspects --- Moral and ethical aspects --- Moral and ethical aspects --- Research --- Research --- Research
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Human biochemistry --- Oncology. Neoplasms --- Human genetics
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Human reproductive technology --- Genetic engineering --- Cloning --- Human genetics
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In Gene Therapy Protocols, leading researchers describe in detail all the essential molecular methods for developing gene transfer systems, along with the methods for introducing genes into specific tissue types either in vivo or ex vivo. These easily reproducible methods range from those for specific viral and nonviral delivery systems, to those concerned with gene delivery to particular tissues. Methods for applying specific therapeutic systems, such as ribozymes and tumor suppressor genes for the treatment of AIDS and cancer, are also included in this authoritative collection. Gene Therapy Protocols is the first major collection of the methods needed for successful gene delivery and subsequent in vivo gene expression, techniques at the center of the many and significant recent advances in the treatment of both genetic and acquired diseases. It will surely become today's indispensable standard reference source for all scientists working to realize the promises of gene therapy.
Human genetics. --- Human Genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Gene therapy --- Genetic Therapy --- Gene Transfer. --- Methodology. --- methods.
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Fueled by rapid advances in the availability of genetic information and the capability to intervene in response to it, a genetic revolution is now underway that has profound implications for all spheres of life. But the ethical issues raised - and sometimes overlooked - by this revolution are glaring. This timely volume, written by scholars and practitioners at the forefront of genetic research-including Francis Collins, Elizabeth Thomson, C. Christopher Hook, Arthur Dyck, Allen Verhey, V. Elving Anderson, Marsha Fowler, and Charles Colson-will help readers assess from a Christian perspective the challenging ethical questions and difficult personal and social decision-making situations raised by today's genetic advancements.
Genetic engineering --- Genetic engineering --- Human genetics --- Human genetics --- Moral and ethical aspects --- Religious aspects --- Christianity --- Moral and ethical aspects --- Religious aspects --- Christianity
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Human embryology --- Epidemiology --- Human genetics --- Pathology of the metabolism --- Antwerp [Province]
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The Lives to Come is at once a concise and accessible guide to the research that scientists are conducting in the field of genetics, a realistic survey of the likely near-term contributions of that research to the treatment of disease, and a thoughtful probing of the deep moral and social issues raised by our increasing abilities to predict the onset of hereditary disease and to make decisions about the kinds of people who will be born. A distinguished scholar of the history and philosophy of science, Philip Kitcher insightfully addresses the practical and philosophical questions posed by the explosion of new discoveries in the field of genetics. As our ability to determine whether individuals are at risk for various diseases and disabilities increases, will medical treatments keep pace? Could widespread use of genetic tests lead to new forms of discrimination in insurance, employment, and how people are viewed by society? How can genetic knowledge improve law enforcement while protecting the rights of the innocent? As prenatal testing provides new opportunities to select the types of people brought into being, how can the abuse of that power be prevented so that we avoid the evils of the eugenic past? If scientists discover a genetic basis for traits deemed socially objectionable, might abortion become a tool for avoiding the birth of "undesirables"? To what extent do new discoveries support the idea that our destinies are written in our genes? More fundamentally, what will become of our self-image as we find out more and more about the mechanisms of our bodies and our brains?
Genetic engineering --- Human genetics --- Moral and ethical aspects --- Human Genome Project
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